Pregnenolone

Product Overview

Pregnenolone is a naturally occurring steroid hormone produced primarily in the adrenal glands. It is often referred to as a “parent hormone” because it serves as a precursor to several key hormones in the body, including:

• Progesterone
• DHEA
• Estrogen
• Testosterone
• Cortisol

At Angel Pharmacy, Pregnenolone Capsules may be supplied as compounded preparations in personalised strengths as prescribed by your healthcare provider.

Pregnenolone should only be used under medical supervision.

What Pregnenolone Is Used For

Pregnenolone may be prescribed in integrative or hormone-focused care plans for:

• Hormone balance support
• Adrenal function support
• Cognitive support in selected cases
• Fatigue management
• Menopausal or andropausal symptom management
• Support in certain neurological or inflammatory conditions

Its use depends on individual hormone testing and clinical assessment.

How Pregnenolone Works

Pregnenolone is synthesised from cholesterol and acts as a building block for multiple downstream hormones.

By supporting pregnenolone levels, treatment may influence:

• Progesterone production
• DHEA levels
• Cortisol regulation
• Sex hormone balance

Because hormone pathways are interconnected, supplementation must be carefully monitored to avoid imbalance.

Individualised Compounding

Pregnenolone Capsules are often compounded in specific strengths tailored to your prescription.

Custom dosing allows:

• Gradual dose titration
• Targeted hormone support
• Reduced risk of over-supplementation

Your prescribing practitioner will determine the appropriate strength and duration of therapy.

Directions for Use

Take exactly as prescribed by your healthcare provider.

General guidance:

• Typically taken once daily
• May be taken in the morning (often preferred due to hormonal rhythms)
• Swallow capsule with water
• Do not adjust dosage without medical advice

Regular follow-up and hormone monitoring may be recommended.

Important Safety Information

Before starting Pregnenolone, inform your doctor if you have:

• Hormone-sensitive conditions
• Breast, ovarian, uterine, or prostate cancer history
• Liver disease
• Thyroid disorders
• Mood disorders
• Cardiovascular disease

Because Pregnenolone influences multiple hormone pathways, unsupervised use may lead to unwanted hormonal shifts.

Possible Side Effects

Side effects vary depending on dosage and individual hormone response.

Potential side effects may include:

• Headache
• Insomnia
• Mood changes
• Irritability
• Acne or skin changes
• Changes in menstrual cycle
• Increased body hair (in some individuals)

If you experience persistent or unusual symptoms, consult your healthcare provider.

Hormone Monitoring

Your doctor may recommend:

• Baseline hormone testing
• Follow-up blood or saliva hormone levels
• Symptom tracking

Monitoring ensures safe and effective treatment.

Pregnancy & Breastfeeding

Pregnenolone should not be used during pregnancy or breastfeeding unless specifically prescribed and closely supervised.

Always inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Drug Interactions

Pregnenolone may interact with:

• Hormone replacement therapies
• Corticosteroids
• Thyroid medications
• Other endocrine therapies

Provide a full medication list to your healthcare provider before starting treatment.

Storage Instructions

• Store below 25°C
• Protect from light and moisture
• Keep in original packaging
• Keep out of reach of children

Frequently Asked Questions

Is Pregnenolone a steroid?

Yes. It is a naturally occurring steroid hormone precursor produced by the body.

Is it the same as progesterone?

No. Pregnenolone is converted into progesterone and other hormones but is not progesterone itself.

How long does it take to notice effects?

Response varies by individual. Some patients notice changes within weeks, while others require longer-term monitoring.

Can I buy Pregnenolone over the counter?

In Australia, compounded hormonal preparations require a valid prescription and medical supervision.

Disclaimer

This information is provided for educational purposes only and does not replace professional medical advice. Pregnenolone Capsules should only be used under the supervision of a qualified healthcare professional.

For personalised advice regarding your prescription, speak with the pharmacists at Angel Pharmacy.