NAD+ Troches 200 MG

Product Overview

NAD+ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme found in all living cells. It plays a critical role in cellular energy production, mitochondrial function, DNA repair, and regulation of metabolic processes. NAD+ levels naturally decline with age and during periods of physiological stress or illness.

NAD+ Troches 200 mg provide a compounded, non-invasive delivery option designed for buccal or sublingual absorption, allowing NAD+ to be absorbed through the oral mucosa. This route may enhance bioavailability while avoiding gastrointestinal degradation associated with oral capsules.

NAD+ supplementation is commonly considered in clinical settings for individuals with documented deficiency, mitochondrial dysfunction, chronic fatigue, or certain metabolic and neurologic conditions, based on provider evaluation. Its use for generalized “anti-aging” or performance enhancement is not FDA-approved and remains investigational.

This medication is available only by prescription and is compounded by specialty pharmacies. All use should occur under the supervision of a licensed healthcare provider.

---

Dosage & Administration

General Dosing Information

Dosing of NAD+ troches is individualized based on clinical need, patient tolerance, and provider judgment. The following represents commonly prescribed ranges and should not replace prescriber instructions.

Typical Adult Dose

• 200 mg once daily, or

• As directed by the prescribing healthcare provider

Troches are typically used once daily, though some clinicians may recommend divided dosing depending on patient response.

---

Administration Instructions

• Place the troche between the cheek and gum or under the tongue

• Allow it to dissolve slowly; do not chew or swallow whole

• Avoid eating or drinking for 10–15 minutes after use to maximize absorption

• Rotate placement sites within the mouth to minimize irritation

• If a dose is missed, follow prescriber guidance; do not double doses

---

Treatment Duration & Monitoring

The duration of NAD+ therapy varies depending on treatment goals and response. Some patients may use NAD+ for short-term metabolic support, while others may continue therapy longer under periodic reassessment.

Monitoring may include:

• Clinical response (energy levels, cognitive function, overall well-being)

• Metabolic markers as indicated

• Tolerance and side effects

If no benefit is observed after a reasonable trial period, therapy may be adjusted or discontinued at the provider’s discretion.

---

Mechanism of Action

NAD+ functions as a central coenzyme in cellular redox reactions, enabling:

• ATP (energy) production in mitochondria

• Activation of sirtuins involved in cellular regulation

• Support of DNA repair enzymes

• Maintenance of normal metabolic and neurologic function

By replenishing NAD+ levels, supplementation may help support cellular energy pathways and metabolic resilience in individuals with documented insufficiency or increased physiologic demand.

The effectiveness of NAD+ supplementation depends on the body’s ability to utilize and transport the molecule at the cellular level, which can vary among individuals.

---

Contraindications & Precautions

NAD+ troches should be used cautiously or avoided in patients with:

• Known hypersensitivity to NAD+ or formulation ingredients

• Active malignancy, unless cleared by an oncologist

• Severe liver disease, unless closely monitored

NAD+ is not intended for use in individuals without a documented medical indication, and it is not approved for athletic enhancement or cosmetic purposes.

Patients should undergo medical evaluation prior to initiation to ensure appropriateness.

---

Drug Interactions

NAD+ may interact indirectly with medications or supplements affecting:

• Cellular metabolism

• Mitochondrial function

• Redox balance

Patients should inform their healthcare provider of all prescription medications, supplements, and over-the-counter products before starting therapy.

Caution is advised when used alongside high-dose niacin or other NAD+ precursors, as combined use may increase the risk of side effects.

---

Adverse Reactions & Side Effects

Common

• Mild oral irritation or discomfort

• Nausea or gastrointestinal upset

• Headache or flushing

Less Common

• Fatigue or restlessness

• Lightheadedness

Most side effects are mild and transient. If irritation occurs, rotating troche placement or adjusting dosing frequency may help.

Patients should discontinue use and contact their provider if significant or persistent symptoms occur.

---

Pregnancy & Breastfeeding

There are no adequate, well-controlled studies evaluating NAD+ supplementation during pregnancy or lactation. Use is not recommended unless the potential benefit clearly outweighs potential risks and is approved by a healthcare provider.

Women who are pregnant, breastfeeding, or planning pregnancy should consult their physician before use.

---

Storage & Handling

• Store troches at room temperature, away from heat, moisture, and direct sunlight

• Keep medication in its original packaging until use

• Do not use if the troche has changed color, texture, or odor

• Keep out of reach of children and pets

Unused or expired medication should be disposed of according to pharmacy instructions.

---

Important Notice

This information is provided for educational purposes only and does not replace medical advice. All dosing and treatment decisions must follow the prescribing healthcare provider’s instructions.