Anastrozole

Product Overview

Anastrozole is a prescription medication classified as an aromatase inhibitor. It works by reducing the body’s production of estrogen.

By lowering estrogen levels, Anastrozole is commonly prescribed for:

• Hormone receptor–positive breast cancer (primarily in postmenopausal women)
• Estrogen suppression during certain fertility or hormone treatments
• Management of estrogen levels in men undergoing testosterone therapy
• Off-label hormonal balance protocols under specialist supervision

At Angel Pharmacy, Anastrozole may be dispensed as commercially available tablets or compounded capsules, depending on your doctor’s prescription and dosing requirements.

How Anastrozole Works

Anastrozole blocks the aromatase enzyme, which converts androgens (like testosterone) into estrogen.

By inhibiting this conversion, it:

• Reduces circulating estrogen levels
• Slows the growth of estrogen-dependent cancer cells
• Helps manage elevated estrogen levels in certain hormone therapy protocols

Because estrogen plays many important roles in the body, careful dosing and medical supervision are essential.

Available Forms

Anastrozole may be supplied as:

• 1mg tablets (standard strength)
• Compounded capsules in personalised doses (if prescribed)

Your healthcare provider will determine the most appropriate formulation and dosage based on your medical needs.

What It May Be Prescribed For

Anastrozole may be prescribed for:

Breast Cancer Treatment

Commonly used in postmenopausal women with hormone receptor–positive breast cancer to reduce recurrence risk.

Hormone Management in Men

In some cases, used alongside testosterone therapy to help manage elevated estrogen levels.

Fertility & Hormonal Protocols

Occasionally prescribed in specialised fertility or endocrine treatment plans.

Use outside approved cancer treatment is determined by your specialist.

Directions for Use

Take exactly as prescribed by your doctor.

Typical guidance:

• Usually taken once daily
• Take at the same time each day
• Swallow whole with water
• Can be taken with or without food

Do not alter your dose unless instructed by your healthcare provider.

Important Safety Information

Before starting Anastrozole, inform your doctor if you have:

• Osteoporosis or low bone density
• Liver disease
• Heart disease
• High cholesterol
• Joint disorders
• History of fractures

Because estrogen supports bone health, long-term estrogen suppression may reduce bone density. Your doctor may monitor bone health during treatment.

Regular blood tests and clinical reviews may be required.

Possible Side Effects

Side effects vary depending on individual response and duration of use.

Common side effects may include:

• Joint stiffness or pain
• Hot flushes
• Fatigue
• Headache
• Nausea
• Mood changes
• Decreased bone density (long-term use)
• Vaginal dryness (in women)

Less commonly:

• Elevated cholesterol
• Bone fractures (with prolonged use)

If you experience severe or unusual symptoms, seek medical advice promptly.

Drug Interactions

Anastrozole may interact with:

• Estrogen-containing medications
• Hormone replacement therapy
• Tamoxifen
• Certain liver-metabolised medications

Always inform your doctor and pharmacist about all medications and supplements you are taking.

Pregnancy & Breastfeeding

Anastrozole is not recommended during pregnancy or breastfeeding.

It is primarily prescribed for postmenopausal women or specific supervised hormone protocols.

If pregnancy occurs while taking Anastrozole, seek immediate medical advice.

Storage Instructions

• Store below 25°C
• Keep in original packaging
• Protect from moisture
• Keep out of reach of children
• Do not use after expiry date

Frequently Asked Questions

Is Anastrozole chemotherapy?

No. It is a hormone therapy medication, not a chemotherapy drug.

Does Anastrozole lower estrogen completely?

It significantly reduces estrogen levels but does not eliminate it entirely.

Can men take Anastrozole?

In certain cases, doctors prescribe it to manage estrogen levels during testosterone therapy. This should always be medically supervised.

Will it affect bone health?

Long-term use may reduce bone density. Monitoring may be recommended.

How long is it taken for?

For breast cancer, it is often prescribed for several years. For hormonal protocols, duration varies based on treatment goals.

Disclaimer

This information is for educational purposes only and does not replace professional medical advice. Anastrozole should only be used under the supervision of a qualified healthcare provider.

For personalised advice regarding your prescription, speak with the pharmacists at Angel Pharmacy.