Naltrexone Capsules

Product Overview

Naltrexone Capsules are a prescription medication used to support treatment for opioid dependence, alcohol use disorder, and certain off-label therapeutic applications. It works by blocking opioid receptors in the brain, reducing cravings and preventing the euphoric effects of opioids.

In lower compounded doses (Low-Dose Naltrexone or LDN), it may also be prescribed for immune modulation and inflammatory support under medical supervision.

Naltrexone capsules are compounded to meet individualized dosing needs as prescribed by your healthcare provider.

What Naltrexone Is Used For

Depending on dosage and clinical direction, Naltrexone may be prescribed for:

Standard-Dose Therapy

• Opioid dependence relapse prevention
• Alcohol use disorder
• Craving reduction support

Low-Dose Naltrexone (LDN) – Off-Label Use

• Autoimmune conditions
• Chronic inflammatory conditions
• Chronic pain disorders
• Immune system modulation
• Fibromyalgia
• Multiple sclerosis support
• Thyroid-related autoimmune conditions

Use is determined by your prescribing provider.

How Naltrexone Works

Naltrexone is an opioid receptor antagonist.

At standard doses:

• Blocks opioid receptors
• Prevents opioid drugs from producing euphoria
• Reduces reinforcing effects of alcohol
• Helps decrease cravings

At low doses (LDN):

• Temporarily blocks opioid receptors
• Stimulates endorphin production
• May help regulate immune system activity
• May reduce inflammation

The mechanism varies depending on the prescribed dose.

Benefits of Naltrexone Therapy

Naltrexone Capsules may help:

• Reduce relapse risk
• Decrease substance cravings
• Support recovery programs
• Improve long-term sobriety outcomes
• Support immune modulation (LDN)
• Reduce chronic inflammation symptoms (off-label)

Results vary based on condition and individual response.

Directions for Use

Take exactly as prescribed by your healthcare provider.

General guidance:

• Take once daily unless otherwise directed
• May be taken with food to reduce nausea
• Swallow capsule whole
• Do not crush or chew

Important: You must be opioid-free before starting standard-dose naltrexone to avoid withdrawal symptoms.

Never start or adjust dosing without medical supervision.

Important Safety Information

Inform your healthcare provider if you:

• Are currently using opioids
• Have liver disease or elevated liver enzymes
• Have kidney impairment
• Are pregnant or breastfeeding
• Have a history of depression or mood disorders

Naltrexone can cause sudden withdrawal if opioids are present in the body.

You must disclose all medications and supplements you are taking.

Possible Side Effects

Common side effects may include:

• Nausea
• Headache
• Fatigue
• Dizziness
• Sleep disturbances
• Decreased appetite

Less common but serious side effects:

• Liver enzyme elevation
• Mood changes
• Depression
• Allergic reactions

Seek medical attention if you experience:

• Severe abdominal pain
• Yellowing of skin or eyes
• Dark urine
• Persistent vomiting

Regular liver monitoring may be recommended.

Monitoring & Follow-Up

Your healthcare provider may:

• Check liver function tests
• Monitor mood changes
• Assess treatment effectiveness
• Adjust dosing as needed
• Confirm opioid-free status before initiation

Routine follow-up is important for safe and effective treatment.

Storage Instructions

• Store at room temperature
• Protect from moisture and light
• Keep container tightly closed
• Keep out of reach of children

Compounded capsules may have specific beyond-use dating provided on the label.

Frequently Asked Questions

What is Low-Dose Naltrexone (LDN)?

LDN refers to doses typically between 0.5 mg and 4.5 mg, prescribed off-label for immune and inflammatory conditions.

Can I take opioids while on naltrexone?

No. Naltrexone blocks opioid effects and may cause withdrawal if opioids are present.

How long does it take to work?

For substance use treatment, craving reduction may occur within days to weeks. For LDN, effects may take several weeks.

Is it addictive?

No. Naltrexone is not habit-forming.

Do I need lab tests?

Liver function testing is commonly recommended before and during treatment.

Disclaimer

Naltrexone Capsules are a prescription medication and must be used under medical supervision. This information is provided for educational purposes and does not replace professional medical advice.

For personalized dosing and compounding options, contact the pharmacists at Angel Pharmacy.