Product Overview
Weight Loss Capsules (Bupropion/Caffeine/Topiramate/Naltrexone/Methylcobalamin 65/20/15/3/1mg) are a compounded oral medication designed to support medically supervised weight management. This multi-ingredient formulation combines medications that target appetite, cravings, energy levels, and metabolic function.
This combination may be prescribed to:
- Support weight loss in adults with overweight or obesity
- Help reduce appetite and food cravings
- Assist with portion control and eating behavior management
- Support energy levels and metabolic activity during weight loss
At Angel Pharmacy, these capsules are compounded based on your provider’s prescription and individualized treatment plan.
How This Combination Works
This formulation brings together multiple active ingredients that work synergistically:
- Bupropion
Helps regulate appetite and may reduce food cravings by affecting brain neurotransmitters. - Caffeine
Supports energy levels and may enhance metabolic rate. - Topiramate
May help reduce appetite and promote a feeling of fullness. - Naltrexone
Works on reward pathways in the brain to help control cravings and eating behaviors. - Methylcobalamin
Supports energy production and nervous system health.
Together, these ingredients target multiple pathways involved in hunger, cravings, and metabolism.
Available Forms
This formulation is supplied as:
- Compounded oral capsules (fixed-dose combination as prescribed)
Your healthcare provider will determine the appropriate dosing schedule and duration based on your individual needs.
What It May Be Prescribed For
Medical Weight Management
Used as part of a structured program to support appetite control and gradual weight reduction.
Craving & Behavioral Control
Helps manage emotional or reward-driven eating patterns.
Energy & Metabolic Support
Supports energy levels during calorie restriction and lifestyle changes.
All use is determined and supervised by a licensed healthcare provider.
Directions for Use
Take exactly as prescribed by your healthcare provider.
Typical guidance:
- Taken orally with water
- May be taken once or twice daily depending on prescription
- Take at the same time each day for consistency
- Follow your provider’s titration or dosing schedule carefully
Do not adjust your dose without medical guidance.
Important Safety Information
Before starting this medication, inform your healthcare provider if you have:
- History of seizures or epilepsy
- High blood pressure or cardiovascular disease
- Depression, anxiety, or other mental health conditions
- Liver or kidney disease
- History of substance use disorder
- Glaucoma or vision problems
This combination may not be suitable for all patients. Regular monitoring may be required during treatment.
Possible Side Effects
Side effects may vary depending on individual tolerance.
Common side effects may include:
- Dry mouth
- Nausea
- Headache
- Insomnia
- Increased heart rate
- Dizziness
- Changes in mood
Less common but serious:
- Seizures (rare, higher risk in predisposed individuals)
- Significant mood changes or anxiety
- Elevated blood pressure
Seek medical attention if you experience severe or unusual symptoms.
Drug Interactions
This formulation may interact with:
- Antidepressants or psychiatric medications
- Opioid-containing medications (due to Naltrexone)
- Stimulants or caffeine-containing products
- Medications affecting seizure threshold
Always inform your healthcare provider of all medications and supplements you are taking.
Pregnancy & Breastfeeding
This medication is not recommended during pregnancy or breastfeeding.
If you become pregnant while using this treatment, discontinue use and consult your healthcare provider immediately.
Storage Instructions
- Store at room temperature (below 25°C)
- Keep in a dry place
- Protect from light and moisture
- Keep out of reach of children
- Do not use after expiry date
Frequently Asked Questions
Is this similar to Contrave?
This formulation includes Bupropion and Naltrexone, which are also found in Contrave, but additional ingredients and dosing may differ.
Will this suppress appetite?
Yes, the combination is designed to help reduce appetite and manage cravings.
How quickly will I see results?
Results vary, but many patients notice changes in appetite and energy levels within a few weeks.
Do I still need diet and exercise?
Yes, this medication is most effective when combined with lifestyle changes including diet and physical activity.
Disclaimer
This information is for educational purposes only and does not replace professional medical advice. This compounded medication should only be used under the supervision of a qualified healthcare provider.
For personalized guidance regarding your prescription, consult the pharmacists at Angel Pharmacy.





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